Wednesday, March 25, 2020

Underreported but Important Covid-19 Facts

Fast Facts:

Similar to: SARS, MERS

Incubation period is on average: 5 Days

Highest risk category: Likely Male, 49-56, Underlying health problem
  • Liver failure is more common among Covid-19 patients that any other form of pneumonia 
  • In good news, CT scans have been shown to potentially diagnose patients with Covid-19
From : Zhao D, Yao F, Wang L, et al. A comparative study on the clinical features of COVID-19 pneumonia to other pneumonias. Clinical Infectious Diseases, ciaa247, March 12, 2020. DOI: https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciaa247/5803302 
  • Tested in 18 pregnancies, (children) --> all women were infected in the third trimester
  • Thankfully, the trial in no evidence of transmission to the child, although it does recommend specific guidelines for delivering under those circumstances (to protect healthcare workers)
https://www.sciencedirect.com/science/article/pii/S0002937820301976?via%3Dihub
  • The virus seems to peak in patients on the 2nd and less-so on the 5th day of experiencing symptoms
  • If you or anyone you know is experiencing this, it's a handy thing to know
  • Also notable, the virus peaked up in smaller amounts on the 11th day since experiencing symptoms
https://www.nejm.org/doi/full/10.1056/NEJMc2001737?query=featured_home
  • More on the symptoms: One article cites,"Twelve patients reported fever (mean, 1.6 days) before hospitalization. Symptoms included cough (46.3%), upper airway congestion (61.5%), myalgia (23.1%), and headache (23.1%)" 
  • Lung damage was temporary in most cases, but in a few instances there was lasting trauma in the area 
https://jamanetwork.com/journals/jama/fullarticle/2761043

Dr. Fauci released an article explaining the diseases relation to the common cold. The majority of coronary viruses produce the common cold. The other, SARS and its offspring MERS, produce fatality rates of 10% and 36% respectively. While this is worse than the (projected) fatality rate of 1% for Covid-19, the vastly superior contamination potential means more people are likely to die outright from this. Fauci explains that while some coronaviruses do cause colds, these are scientifically removed from classification with those other strains due to their severity in humans. 

https://www.cdc.gov/coronavirus/2019-ncov/downloads/jama_paules_2020_vp_200006.pdf